Wednesday, March 21, 2012

B - Publication of NIH funded clinical trials

Ross JS, Tse T, Zarin DA et al. Publication of NIH funded trials registered in ClinicalTrials.gov: cross sectional analysis. British Medical Journal 2012;344:d7292

The US FDA Amendment Act of 2007 requires that clinical trials subject to regulation be registered and reported in ClinicalTrials.gov, and this is - according to the ICMJE - a requisite for publication. This legislation aims at improving the accessibility of clinical trial results. The results of this study showed that fewer than half of clinical trials funded by NIH and registered within ClinicalTrials.gov were published in a peer-reviewed biomedical journal indexed by Medline within 30 months trial completion. The median time of publication was 51 months after trial completion, and a third of trials remained unpublished.

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