Lehman R, Loder E. Missing clinical trial data. British Medical Journal 2012;344:d8158
A large proportion of evidence from human trials is unreported, and much of what is reported is done inadequately. Missing data about harm in trials can harm patients, and incomplete data about benefit can lead to futile costs to healthy systems. Some articles are listed that look closely at the extent, causes, and consequences of unpublished evidence from clinical trials. They show that the current situation is a disservice to research participants, patients, and health systems. The authors advocate for a retroactive disclosure of all clinical trial data and for developing better systems for the future.