Khoury MJ, Ioannidis JPA. Big data meets public health. Science 346(6213):1054
The term “Big Data” refers to volumes of large, complex, linkable information. Beyond genomics and other “omic” fields, Big Data includes medical, environmental, financial, geographic, and social media information. This swell of data will continue to grow. Big Data can improve health by providing insights into the causes and outcomes of disease, better drug targets for precision medicine, and enhanced disease prediction and prevention. But "Big Error" can plague Big Data. The combination of a strong epidemiologic foundation, robust knowledge integration, principles of evidence-based medicine, and an expanded translation research agenda can put Big Data on the right course.