Wednesday, March 12, 2014

B - Japanese randomized controlled trials

Yoneoka D, Hisashige A, Ota E, et al. Are Japanese randomized controlled trials up to the task? A systematic review. PLoS ONE 2014;9(3):e90127
(doi: 10.1371/journal.pone.0090127)

The number of published randomized controlled trials (RCTs) is rapidly increasing worldwide. This study identified the number of all Japanese RCTs published in Japan in 2010, it assessed their general characteristics and quality and analyzed factors related to their quality. Despite a considerable number of RCTs conducted in Japan, their quality is not satisfactory in some domains. On the other hand, there are high-quality, non-indexed RCTs. The full disclosure of trial information and quality control of clinical trials are urgently needed in Japan.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0090127

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